Because it is injected straight into the bloodstream, it can be used to supply vitamin B 12 to people who cannot absorb this vitamin through the intestine. Labeler Name: American Regent, Inc. Thus, in the current study, the influence of cyanocobalamin (CNCBL) or methylcobalamin (MECBL) ingestion on … Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for CYANOCOBALAMIN. Cyanocobalamin is indicated for vitamin B 12 deficiencies due to malabsorption which may be associated with the following conditions:. Most people get enough vitamin B 12 from their food, but if you have had stomach surgery, or certain diseases of the intestines, or a restricted diet, you may not absorb enough vitamin B 12.. Leber's hereditary optic atrophy. This drug can be used in both humans and other animal species that have a specific indication for its use as recommended by their doctor or veterinarian. Cyanocobalamin is an over-the-counter medication. Cyanocobalamin is used to treat vitamin B12 deficiency in people with pernicious anemia or other conditions such as folic acid deficiency, pregnancy, thyroid problems, stomach and intestinal disorders, bleeding, liver or kidney disease, parasite infection, or cancer. Cyanocobalamin injection is injected into a muscle or under the skin. Medscape - Indication-specific dosing for vitamin B12, Athlete (cyanocobalamin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & … Davis Drug Guide PDF. Before using cyanocobalamin, tell your doctor or pharmacist if you are allergic to it; or to cobalt; or if you have any other allergies. Cyanocobalamin is an inexpensive drug used to treat people who can't absorb vitamin B12. Nascobal (cyanocobalamin) Nasal Spray is indicated for the maintenance of normal hematologic status in pernicious anemia patients who are in remission following intramuscular vitamin B 12 therapy and who have no nervous system involvement.. Nascobal (cyanocobalamin) Nasal Spray is also indicated as a supplement for other vitamin B 12 deficiencies, including: It is one of eight B vitamins.It is a cofactor in DNA synthesis, in both fatty acid and amino acid metabolism. Type Small Molecule Groups Approved Structure Cyanocobalamin Injection, USP is a sterile solution of cyanocobalamin for intramuscular or subcutaneous injection. Metabolism: Cyanocobalamin and hydroxocobalamin are metabolized in the liver. Cyanocobalamin can lead to optic nerve damage (and possibly blindness) in people with Leber's disease. Cyanocobalamin Co-57 is a diagnostic agent used for the diagnosis of pernicious anemia and other conditions related to malabsorption of vitamin B12. Cyanocobalamin is indicated for vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia; Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy What is a good dosage and how often? Vegetarian people may also acquire this deficiency. past history of complete removal of stomach. Cyanocobalamin, or vitamin B12, is a B-vitamin. Initial: 100 mcg IM qDay for > 2 weeks (1-5 mg total dose) High doses of vitamin B12 (cyanocobalamin) may be therapeutically effective to treat neurological alterations secondary to a wide range of disease states. Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacterial overgrowth, total or partial gastrectomy. Cyanocobalamin injection is used to treat or prevent vitamin B12 deficiency caused by the following conditions: Addisonian (pernicious) anemia.
Dosing and Route. Cyanocobalamin may also be used for purposes not listed in this medication guide. Cyanocobalamin is a man-made form of vitamin B12 used to treat low levels (deficiency) of this vitamin. Cyanocobalamin is used to treat vitamin B12 deficiency in people with pernicious anemia and other conditions. As a hematopoietic agent, it is converted to coenzyme B12 needed in the conversion of methylmalonate to succinate and production of methionine from homocysteine, a reaction requiring folate. INDICATIONS AND USAGE. pernicious anaemia) as it is retained in the body longer than cyanocobalamin. Should be taken on an empty stomach. Includes dosages for B12 Nutritional Deficiency, Pernicious Anemia and … Cyanocobalamin is a prescription and over-the-counter man-made form of vitamin B12 used to prevent and treat low blood levels of vitamin B12.Most people get enough vitamin B12 from their diet. Cyanocobalamin (vitamin B12 or cobalamin) is a vitamin supplement used to treat systemic deficiencies. Descriptions. Consumer information about the supplement cyanocobalamine (Cobal, Cyanoject, Vitamin B-12) used to treat vitamin deficiencies from malabsorption like pernicious anemia, certain cancers, folic acid deficiency, and tapeworm infestation. Vitamin B12, alternatively known as cyanocobalamin, is a member of the B vitamin family. It also helps with the metabolism of fats and carbohydrates. This medicine is to be given only by or under the direct supervision of your doctor. Cyanocobalamin is especially dangerous to those with liver problems, renal failure, and smokers, because in those people the cyanide can’t be eliminated effectively. It’s also dangerous for pernicious anemia patients or anyone else with high homocysteine levels, because it may deplete the body of glutathione,... The name cyanocobalamin is owing to the fact it has a cyanide group attached to the molecule. Your dose needs may … Benzyl Alcohol, 1.5%, is present as a preservative. Initially 1 mg every 2–3 days for 11 doses; maintenance 1 mg every month. Vitamin B12 deficiency of dietary origin. Vitamin B-12 (as Cyanocobalamin) Purpose. If every single bit of cyanide in a 500 mcg tablet were to give up its cyanide, you'd have about 9.6 mg of cyanide. 25 mcg, 50 mcg, 100 mcg, 250 mcg tablets; 400 mcg/unit, 500 mcg/0.1 mL nasal gel; 500 mcg/0.1 mL nasal spray. What is Cyanocobalamin (Cyanocobalamin)? Usually, the supplement takes 48-72 hours to start working. Each mL contains 1000 mcg Cyanocobalamin. Also is there such a thing as an injectable multivitamin? INDICATIONS AND USAGE. Hydrochloric acid and/or sodium hydroxide may have been added during manufacture to adjust the pH (range 4.5-7.0). This medicine is to be given only by or under the direct supervision of your doctor. Cyanocobalamin injection is in a class of medications called vitamins. The cyanocobalamin nasal spray is indicated for the maintenance of vitamin B12 concentrations after normalization with intramuscular vitamin B12 therapy in patients with deficiency of this vitamin who have no nervous system involvement Label.. Use Vitamin B-12 (Cyanocobalamin (Injection)) exactly as directed on … Doses are taken once daily. INDICATIONS AND USAGE Cyanocobalamin is indicated for Vitamin B deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy Cobalamin should be supplemented whenever serum cobalamin concentration is in the low normal range (i.e., less than approximately 400 ng/L) in both dogs and cats. Uses. Excretion: In healthy people receiving only dietary vitamin B 12 , about 3 to 8 mcg of the vitamin is secreted into the GI tract daily, mainly from bile, and all but about 1 mcg is reabsorbed; less … Indications. Dosage pernicious anemia: 1000 mcg/day for 7 days, then every other day for 7 days, then every 3-4 das for 2-3 wks. Remember that 500 mcg, although not an uncommon dosage, is still about 200 times the RDA. This Medicines Q&A outlines what oral vitamin B12 (cyanocobalamin) preparations are available and associated prescribing considerations. Take between meals. 1000mcg/mL (30mL) Cyanide Poisoning (Off-label) 70 mg/kg (usually 5 g) IV infusion over 15 minutes; additional dose of 35 mg/kg IV may be given depending on severity of poisoning and clinical response. 50–150 micrograms daily, dose to be taken between meals. Dosage: In patients with Addisonian (pernicious) anemia, parenteral therapy with cyanocobalamin is the recommended method of treatment and will be required for the remainder of the patient's life. It may be given to you for other reasons. Vitamin B12 – The Fundamentals. Cyanocobalamin is used to treat vitamin B12 deficiency in people with pernicious anemia and other conditions. Cyanocobalamin may also be used for purposes not listed in this medication guide. Cyanocobalamin is a manufactured version of vitamin B12. Cyanocobalamin tablets should be taken with water and between meals. Uses of Cyanocobalamin Injection: It is used to help with some kinds of anemia. Side effects, drug interactions, dosage, storage, and pregnancy and breastfeeding safety information should is provided. Patients with inflammatory bowel disease (IBD) are usually advised to supplement various types of vitamin B 12, because vitamin B 12 is generally absorbed in the colon. You can get it from your food or supplements, but sometimes there may not be enough vitamins in what you eat. It is usually injected by a healthcare provider in an office or clinic. The NDC Code 0517-0032-25 is assigned to a package of 25 vial, multi-dose in 1 tray > 10 ml in 1 vial, multi-dose (0517-0032-01) of Cyanocobalamin, a human prescription drug labeled by American Regent, Inc.. 1,000 mcg IM daily for 2 to 7 days, then 100 mcg IM/subcutaneously weekly for 4 weeks, then monthly until recovery has been recommended and used in children. The recommended dosage for pure Vitamin B12 ranges from 100mcg - 1000mcg depending on what you are taking the product for. ringing in the ears. Hydroxocobalamin 1mg administered intramuscularly (IM) is the preferred method of treatment for non-diet-related vitamin B12 deficiency (e.g. Most people get enough vitamin B12 from their diet. Vitamin B 12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. Vitamin deficiency: 30 mcg/day for 5-10 days, then 100-200 mcg/month Cyanocobalamin injection will supply you with enough vitamin B12 only as long as you receive injections regularly. Indications & Usage. CYANOCOBALAMIN INJECTION Monographs. Chemically it belongs to "corrinoids," and it is a crystallizable cobalt-complex. Cyanocobalamin dosage? Individuals who have had gastrointestinal surgery Each vial also contains Sodium Chloride, 0.9%. Fish tapeworm infestation. Cyanocobalamin Dosage & Precautions. Generic cyanocobalamin is covered by some Medicare and insurance plans, but some pharmacy coupons and cash prices may be lower. Your dose needs may change if you become pregnant, if you breastfeed, or if you eat a vegetarian diet. Drug interactions with cyanocobalamin include: Para-aminosalicylic acid, colchicine, biguanides, neomycin, cholestyramine, potassium chloride, methyldopa, and cimetidine — reduce the absorption of cyanocobalamin. Dose: 1000 mcg SC/IM qd x1wk, then qwk x1mo, then maintenance tx; Alt: 100 mcg SC/IM qd x1wk, then qod x2wk, then q3-4 days x2-3wk or until complete remission, then maintenance tx; Info: give intradermal skin test before use if hypersensitivity risk. Dosage Guidelines & Tips How to take Vitamin B-12 (Cyanocobalamin (Injection))? Benzyl Alcohol, 1.5%, is present as a preservative. Folic acid deficiency. LMTHF-Pyridoxine-Cyanocobalamin 2 Mg-1.13 Mg-25 Mg Tablet Generic Name(S): B12-levomefolate calcium-B6 View Free Coupon Vitamin B12 is used in the growth of healthy blood cells, nerve cells, and proteins in the body. Cyanocobalamin is indicated for vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology , dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy A lack of treatment adherence was admitted by 46.6% of patients in who the oral route failed. The generic name of Cyanocobalamin is cyanocobalamin. This medicine is used to … Vitamin B-12 Cyanocobalamin 1,000 mcg / mL Injection Multiple Dose Vial 10 mL. INDICATIONS. Worm infestation. The product's dosage form is injection, solution and is administered via intramuscular form. What Cyanocobalamin Tablets are and what they are used for. INDICATIONS AND USAGE Cyanocobalamin is indicated for Vitamin B deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy Each mL contains 1000 mcg cyanocobalamin. Generic Name Cyanocobalamin Co-57 DrugBank Accession Number DB09385 Background. Cyanocobalamin is a synthetic form of vitamin B12 that can be converted to the natural forms methylcobalamin and adenosylcobalamin. Click to view Polynerv 250/Polynerv 500 detailed prescribing information. Used in the treatment of anemia. inflammation of the stomach called atrophic gastritis. Learn about drug imprint, side effects, uses (treating), dosage, interaction, overdose, and warnings. Vitamin B12 Deficiency. 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